Outcomes for ER-positive CHEK2 c.1100delC breast cancer patients compared with breast cancer patients without the variant
In our study, with more recent years of diagnosis and treatment, we found no difference in prognosis, as opposed to previous studies. Further research is needed to validate our findings.
Authors
- Marjanka K. Schmidt (ORCID: https://orcid.org/0000-0002-2228-429X)
- Nyrée Smallenbroek
- Ingrid A Boere (ORCID: https://orcid.org/0000-0002-4857-6346)
- Maartje A. C. Schreurs (ORCID: https://orcid.org/0000-0002-1826-5344)
- Janet R. Vos (ORCID: https://orcid.org/0000-0001-8802-7002)
- Linda de Munck (ORCID: https://orcid.org/0000-0002-2930-509X)
- B.A.M. Heemskerk-Gerritsen
- Geertruida H. de Bock (ORCID: https://orcid.org/0000-0003-3104-4471)
- Muriel A Adank
- Liselotte P. van Hest (ORCID: https://orcid.org/0000-0002-9373-6601)
- Agnes Jager
- Antoinette Hollestelle
- Maartje J. Hooning
- Margreet G E M Ausems
- Christi J. van Asperen
- Kim J A F van Kaam
- Irma van de Beek
Institutions
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- University of Groningen (NL)
- Utrecht University (NL)
- Leiden University Medical Center (NL)
- Radboud University Medical Center (NL)
- The Netherlands Cancer Institute (NL)
- Maastricht University (NL)
- Oncode Institute (NL)
- Netherlands Comprehensive Cancer Organisation (NL)
- Erasmus MC Cancer Institute (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- The Breast
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1016/j.breast.2025.104666
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Amsterdam University Medical Centers
- Universiteit Leiden
- Rijksuniversiteit Groningen
- Radboud Universiteit
- Universiteit Maastricht
- Erasmus Medisch Centrum
- Maastricht Universitair Medisch Centrum
- Leids Universitair Medisch Centrum
- Radboud Universitair Medisch Centrum