Platelet concentrates in periodontics: a journey through platelet-rich plasma, platelet-rich fibrin and their therapeutic uses: a literature update
Its unique three-dimensional fibrin network supports cellular migration and acts as a framework for tissue regeneration, offering gradual release of growth factors like transforming growth factor-beta and platelet-derived growth factor. Advanced forms, such as injectable PRF, are developed to enhance clinical outcomes by promoting fibroblast migration and tissue regeneration. This review explores the various types of platelet concentrates, their preparation methods, and their applications in periodontal therapy. It highlights the potential of PRF in enhancing periodontal regeneration, offering a comprehensive overview of current advancements and future directions in this field.
Authors
- Shan Sainudeen (ORCID: https://orcid.org/0000-0003-1700-8618)
- Suheel Manzoor Baba (ORCID: https://orcid.org/0000-0002-9729-883X)
- Suraj Arora (ORCID: https://orcid.org/0000-0002-1963-8931)
- Shafait Ullah Khateeb (ORCID: https://orcid.org/0000-0003-3505-2276)
- Ahmed Babiker Mohamed Ali (ORCID: https://orcid.org/0000-0002-7260-0764)
- Gotam Das (ORCID: https://orcid.org/0000-0001-9506-6456)
- Vishakha Grover (ORCID: https://orcid.org/0000-0001-7492-0676)
- Supreet Kaur (ORCID: https://orcid.org/0000-0002-0232-8769)
- Priyanka Saluja
- A Khalil
Institutions
- University of Alberta (CA)
- Panjab University (IN)
- King Khalid University (SA)
- Kamineni Institute of Dental Sciences (IN)
Publication Details
- Journal
- Current Opinion in Hematology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1097/moh.0000000000000903
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00