<i>Leiotulus aureus</i> (Sm.) Pimenov &amp; Ostr.: the essential oil chemical composition of the accession growing wild in North Macedonia

The genus <i>Leiotulus</i> Ehrenb., included within the Apiaceae family, has a limited geographical distribution. It has a fairly complex nomenclatural history as it has been considered as a synonym for <i>Malabaila</i> Hoffm. <i>Leiotulus aureus</i> (Sm.) Pimenov & Ostr., native To East Mediterranean area, is a plant utilised in the Turkish ethnomedicine. This is the first report regarding the chemical composition of the essential oil from aerial parts of this plant, collected in North Macedonia. The essential oil (<b>La</b>) was characterised by large amounts of phenylpropanoids (50.0%) and esters (33.5%), being myristicin (42.8%) and octyl butyrate (32.0%) the main oil constituents. A comparison with previously published results regarding essential oils of genus <i>Leiotulus</i> was discussed. Furthermore, reviews of the use of the <i>Leiotulus</i> species in the popular medicine, as well as of the chemical composition of their essential oils have been carried out.