Early Post-Thrombectomy MRI Markers

This observational study systematically characterized MRI markers at serial follow-up early after EVT. The heterogeneous and dynamic evolution observed during the hours and days after EVT in most patients suggests further opportunity to intervene, with early incomplete reperfusion and reperfusion injury as prognostic differentiators. Our findings can serve as a roadmap for designing future clinical trials to develop adjunctive therapies targeting these imaging markers.

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Publication Details

Journal
Neurology
Published
2025-11-24
DOI
https://doi.org/10.1212/wnl.0000000000214418
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
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article

Early Post-Thrombectomy MRI Markers

Jill B. De Vis, Lawrence L. Latour, Marie L. Luby, Victoria Uche et al.
Neurology
Acute Ischemic Stroke Management
article

Early Post-Thrombectomy MRI Markers

Jill B. De Vis, Lawrence L. Latour, Marie L. Luby, Victoria Uche, Michael Kline, Amie W. Hsia, Shannon Burton, Rebecca F. Gottesman, José G. Merino, Carolyn A. Lomahan, Clinton B. Wright, Leila Thomas, Meghan Hildreth, Amiraj Dhawan, John K. Lynch, Rainier Cabatbat, Sana Somani, Veronica Craft, Yongwoo Kim, Bailey Sowers, Maureen Pajunar
article en

Abstract

This observational study systematically characterized MRI markers at serial follow-up early after EVT. The heterogeneous and dynamic evolution observed during the hours and days after EVT in most patients suggests further opportunity to intervene, with early incomplete reperfusion and reperfusion injury as prognostic differentiators. Our findings can serve as a roadmap for designing future clinical trials to develop adjunctive therapies targeting these imaging markers.

NeurologyVol. 105(12)
MedStar Washington Hospital Center (US), Georgetown University (US), Suburban Hospital (US), Georgetown University Medical Center (US), Washington Hospital (US), Karolinska Institutet (SE), National Institute of Neurological Disorders and Stroke (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 53%
Acute Ischemic Stroke Management
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Early Post-Thrombectomy MRI Markers — Jill B. De Vis, Lawrence L. Latour, et al. · Neurology (2025) | TGRS Research Map | TGRS