Detection of Titin-Associated Electrocardiography Features in Dilated Cardiomyopathy Using Conventional and Deep Neural Network Analysis

Conventional ECG and DNN analyses demonstrated similar good predictive performance in distinguishing TTNtv from gene-elusive DCM patients, emphasizing their potential as clinical tools to guide targeted genetic testing.

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Publication Details

Journal
JACC. Clinical electrophysiology
Published
2025-11-24
DOI
https://doi.org/10.1016/j.jacep.2025.10.006
Primary Topic
Cardiomyopathy and Myosin Studies
Type
article
Field-Weighted Citation Impact
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article

Detection of Titin-Associated Electrocardiography Features in Dilated Cardiomyopathy Using Conventional and Deep Neural Network Analysis

Job A.J. Verdonschot, Nerea Mora Ayestarán, René van Es, Rutger R van de Leur et al.
JACC. Clinical electrophysiology
Cardiomyopathy and Myosin Studies
article

Detection of Titin-Associated Electrocardiography Features in Dilated Cardiomyopathy Using Conventional and Deep Neural Network Analysis

Job A.J. Verdonschot, Nerea Mora Ayestarán, René van Es, Rutger R van de Leur, Kevin Vernooy, Max F.G.H.M. Venner, Steven A. Muller, Marisol Soria, Saskia N. van der Crabben, Pablo García‐Pavía, Natàlia Ramos, Stéphane Heymans, Esther González-López, Rachel M.A. ter Bekke, Anneline S.J.M. te Riele, Ping Wang, Sophie L V M Stroeks, Nina J Beelen, Astrid B M Heymans, Isa M E Faassen
article en

Abstract

Conventional ECG and DNN analyses demonstrated similar good predictive performance in distinguishing TTNtv from gene-elusive DCM patients, emphasizing their potential as clinical tools to guide targeted genetic testing.

JACC. Clinical electrophysiologyVol. 12(2)
Maastricht University Medical Centre (NL), University Medical Center Utrecht (NL), Maastricht University (NL), Hospital Universitario Puerta de Hierro Majadahonda (ES), Centro de Investigación Biomédica en Red (ES), ERN GUARD-Heart (NL)
Openalex Percentile: Top 47%
Cardiomyopathy and Myosin Studies
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