Iatrogenic Botulism Following Botulinum Toxin Injection in a Child With Cerebral Palsy: A Case Report
BackgroundBotulinum toxin is widely used for the treatment of spasticity in pediatric patients with cerebral palsy. Although regarded as safe, rare but severe systemic complications, such as iatrogenic botulism, may arise.Case PresentationWe present the case of an 8-year-old boy with cerebral palsy who experienced global muscle weakness, bilateral ptosis, dysphagia, and respiratory distress after botulinum toxin A (Dysport). The clinical presentation was consistent with iatrogenic botulism. The patient was administered botulinum antitoxin, resulting in a gradual enhancement of the condition. Sequential clinical photos depict the progression of the sickness and subsequent recovery, which led to progressive improvement.ConclusionIatrogenic botulism must be contemplated in individuals exhibiting new-onset bulbar or respiratory symptoms after botulinum toxin injection. Timely identification and prompt commencement of antitoxin treatment are essential for positive outcomes.
Authors
- Serap Tomruk Sütbeyaz (ORCID: https://orcid.org/0000-0002-1992-7178)
- Hüseyin Per (ORCID: https://orcid.org/0000-0001-9904-6479)
- Selcan Öztürk (ORCID: https://orcid.org/0000-0002-3517-2983)
Institutions
- University of Health Science (KH)
- Kayseri Eğitim ve Araştırma Hastanesi (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- University of Health Sciences (SO)
- Erciyes University (TR)
Publication Details
- Journal
- Journal of Child Neurology
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1177/08830738251395996
- Primary Topic
- Botulinum Toxin and Related Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00