Within-individual variation of C-reactive protein (CRP) measurements in primary care: A retrospective cohort study

Estimated within-individual variation in this analysis of real-world data is very high and is higher than previously reported. Variation increases with patient median CRP, that is with more severe disease status. This has important implications for the diagnosis, monitoring and clinical decision-making for inflammatory disease.

Authors

Institutions

Publication Details

Journal
PLoS ONE
Published
2025-11-24
DOI
https://doi.org/10.1371/journal.pone.0337221
Citations
1
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
1.05
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Within-individual variation of C-reactive protein (CRP) measurements in primary care: A retrospective cohort study

Tom Marshall, Alex Gough, Alice Sitch
1 citations
PLoS ONE
Inflammatory Biomarkers in Disease Prognosis
1.05
article

Within-individual variation of C-reactive protein (CRP) measurements in primary care: A retrospective cohort study

Tom Marshall, Alex Gough, Alice Sitch
article en
1 citations

Abstract

Estimated within-individual variation in this analysis of real-world data is very high and is higher than previously reported. Variation increases with patient median CRP, that is with more severe disease status. This has important implications for the diagnosis, monitoring and clinical decision-making for inflammatory disease.

PLoS ONEVol. 20(11)
NIHR Birmingham Biomedical Research Centre (GB), University of Birmingham (GB)
Openalex Percentile: Top 16%
Inflammatory Biomarkers in Disease Prognosis
1.05
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.