Within-individual variation of C-reactive protein (CRP) measurements in primary care: A retrospective cohort study
Estimated within-individual variation in this analysis of real-world data is very high and is higher than previously reported. Variation increases with patient median CRP, that is with more severe disease status. This has important implications for the diagnosis, monitoring and clinical decision-making for inflammatory disease.
Authors
- Tom Marshall (ORCID: https://orcid.org/0000-0001-9277-5214)
- Alex Gough (ORCID: https://orcid.org/0000-0001-6954-7408)
- Alice Sitch (ORCID: https://orcid.org/0000-0001-7727-4497)
Institutions
- NIHR Birmingham Biomedical Research Centre (GB)
- University of Birmingham (GB)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1371/journal.pone.0337221
- Citations
- 1
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.05