Microbiota-supportive diets and hyperlipidemia: The mediating role of systemic inflammation

Microbiota-oriented dietary patterns, as captured by the DI-GM, are inversely associated with hyperlipidemia in U.S. adults. These findings highlight the value of integrating microbiome-relevant dietary assessment into lipid management strategies. Partial mediation by systemic inflammation underscores a potential mechanistic link warranting further investigation through longitudinal and interventional studies.