Association of high-density lipoprotein cholesterol with the top 10 causes of death
HDL-C is nonlinearly and sex-specifically associated with the top ten global causes of death. Both low and high HDL-C confer increased risk through different mechanisms. These findings highlight the importance of evaluating HDL functionality rather than just quantity in future research and clinical care.
Authors
- Chenxi Song (ORCID: https://orcid.org/0000-0003-1943-7037)
- Shanshan Shi (ORCID: https://orcid.org/0000-0003-4970-3615)
- Kefei Dou (ORCID: https://orcid.org/0000-0002-8372-6338)
- Zixiang Ye
- Zhangyu Lin
- Yanjun Song
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fu Wai Hospital (CN)
- State Key Laboratory of Cardiovascular Disease
- Beihang University (CN)
Publication Details
- Journal
- European Journal of Preventive Cardiology
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1093/eurjpc/zwaf749
- Citations
- 2
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 2.59