Multimodal molecular testing provides prognostic value for heart transplant recipients
Patients with dual positive GEP and dd-cfDNA are at increased risk for subsequent GD and CV death, even in the absence of histological evidence of rejection, indicating circulating multimodal molecular evidence of rejection provides prognostic information not detected by histology.
Authors
- Shelley Hall (ORCID: https://orcid.org/0000-0002-4894-396X)
- Kiran Kaur Khush (ORCID: https://orcid.org/0000-0001-9697-5926)
- Nir Y. Uriel (ORCID: https://orcid.org/0000-0003-2301-3587)
- David A. Baran (ORCID: https://orcid.org/0000-0002-7754-9953)
- Palak Shah (ORCID: https://orcid.org/0000-0001-8175-168X)
- Kris Oreschak (ORCID: https://orcid.org/0000-0003-2947-8967)
- Nirav Raval (ORCID: https://orcid.org/0000-0002-8204-9486)
- Ashwin Ravichandran (ORCID: https://orcid.org/0000-0003-2571-4432)
- Sean Pinney (ORCID: https://orcid.org/0000-0002-0268-7817)
- Chun‐Po Steve Fan (ORCID: https://orcid.org/0000-0002-1278-0118)
- J. Teuteberg
- Gabriel Sayer (ORCID: https://orcid.org/0000-0003-1701-1593)
- Snehal R. Patel (ORCID: https://orcid.org/0000-0003-4987-051X)
- E.C. DePasquale (ORCID: https://orcid.org/0000-0002-0638-5218)
- Ann Nguyen (ORCID: https://orcid.org/0000-0002-6572-4099)
- Jeremy Kobulnik (ORCID: https://orcid.org/0000-0002-5417-2866)
- Sijia Wang (ORCID: https://orcid.org/0000-0003-2573-5030)
Institutions
- Twitter (United States) (US)
- University of Southern California (US)
- Montefiore Medical Center (US)
- Cardiovascular Institute of the South (US)
- Columbia University Irving Medical Center (US)
- AdventHealth Orlando (US)
- Veterans Health Administration (US)
- St Vincent Hospital (US)
- Inova Fairfax Hospital (US)
- Baylor University Medical Center (US)
- University of Chicago (US)
- Cleveland Clinic Florida (US)
- Medical Data Exchange (US)
- Translational Research Institute for Metabolism and Diabetes (US)
- Stanford Medicine (US)
- PAX Scientific (United States) (US)
- Alaska Heart and Vascular Institute (US)
- Stanford University (US)
Publication Details
- Journal
- The Journal of Heart and Lung Transplantation
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1016/j.healun.2025.11.013
- Citations
- 2
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- CareDx