Performance Study of Noninvasive Salivary Biomarkers in Laryngopharyngeal Reflux

Noninvasive diagnosis of LPRD is possible, based on a single saliva collection, although our cut-offs should be evaluated in further studies. A reproducible analytical protocol has been obtained. Salivary elastase, cholesterol, and pH show clinical utility for the presence of duodeno-gastric reflux in LPRD patients.

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Publication Details

Journal
The Journal of Applied Laboratory Medicine
Published
2025-11-24
DOI
https://doi.org/10.1093/jalm/jfaf171
Citations
1
Primary Topic
Gastroesophageal reflux and treatments
Type
article
Field-Weighted Citation Impact
1.81
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article

Performance Study of Noninvasive Salivary Biomarkers in Laryngopharyngeal Reflux

Nathalie De Vos, Vinciane Muls, Sven Saussez, Hafid Dahma et al.
1 citations
The Journal of Applied Laboratory Medicine
Gastroesophageal reflux and treatments
1.81
article

Performance Study of Noninvasive Salivary Biomarkers in Laryngopharyngeal Reflux

Nathalie De Vos, Vinciane Muls, Sven Saussez, Hafid Dahma, Jerome Rene Lechien, Anne Trelcat, Stéphane Hans, Mathieu Antoine
article en
1 citations

Abstract

Noninvasive diagnosis of LPRD is possible, based on a single saliva collection, although our cut-offs should be evaluated in further studies. A reproducible analytical protocol has been obtained. Salivary elastase, cholesterol, and pH show clinical utility for the presence of duodeno-gastric reflux in LPRD patients.

The Journal of Applied Laboratory MedicineVol. 11(2)
University of Mons (BE), Université Libre de Bruxelles (BE), Université Paris-Saclay (FR), Science and Engineering Research Board (IN), Universitair Ziekenhuis Brussel (BE), European Biodiesel Board (BE), Centre Hospitalier Universitaire de Saint-Pierre (BE)
Openalex Percentile: Top 11%
Gastroesophageal reflux and treatments
1.81
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Performance Study of Noninvasive Salivary Biomarkers in Laryngopharyngeal Reflux — Nathalie De Vos, Vinciane Muls, et al. · The Journal of Applied Laboratory Medicine (2025) | TGRS Research Map | TGRS