Disproportionality analysis of biliary adverse events associated with fibrates using the JADER and FAERS databases
A significant signal for biliary ADEs was detected for fibrates in both databases, with a particularly consistent association for pemafibrate. Regular hepatobiliary monitoring and individualized patient management are recommended.
Authors
- Kiyoko Nagura
- Taro Watanabe
- Naoto Okada (ORCID: https://orcid.org/0000-0003-2476-9191)
- Hidenori Sagara
- Shiro Watanabe
Institutions
- Yamaguchi University Hospital (JP)
- Yamaguchi Prefecture Central Hospital (JP)
- Sanyo-Onoda City University (JP)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-24
- DOI
- https://doi.org/10.3389/fphar.2025.1700589
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00