Beyond Traditional Risk Factors: Inflammation, Asymmetric Dimethylarginine, and N-Terminal pro–B-Type Natriuretic Peptide Predict Cardiovascular Risk in Chronic Kidney Disease

Both traditional and non-traditional factors contribute to the CV burden in CKD. Biomarkers of inflammation and endothelial dysfunction (IL-6, ADMA) are independent predictors of NT-proBNP and provide prognostic value beyond classical determinants. Incorporating these biomarkers into risk stratification models may improve prediction and guide innovative therapeutic strategies to reduce CV morbidity and mortality in CKD.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2025-11-24
DOI
https://doi.org/10.7759/cureus.97654
Primary Topic
Heart Failure Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Beyond Traditional Risk Factors: Inflammation, Asymmetric Dimethylarginine, and N-Terminal pro–B-Type Natriuretic Peptide Predict Cardiovascular Risk in Chronic Kidney Disease

Somida Kuka, Elizana Zaimi, Ledio Collaku, Margarita Resuli et al.
Cureus
Heart Failure Treatment and Management
article

Beyond Traditional Risk Factors: Inflammation, Asymmetric Dimethylarginine, and N-Terminal pro–B-Type Natriuretic Peptide Predict Cardiovascular Risk in Chronic Kidney Disease

Somida Kuka, Elizana Zaimi, Ledio Collaku, Margarita Resuli, Eneida Hoxha, Saimir Seferi, Anyla Bulo, Pandush Pojani, Xhesika Habilaj, Matilda Kambo
article en

Abstract

Both traditional and non-traditional factors contribute to the CV burden in CKD. Biomarkers of inflammation and endothelial dysfunction (IL-6, ADMA) are independent predictors of NT-proBNP and provide prognostic value beyond classical determinants. Incorporating these biomarkers into risk stratification models may improve prediction and guide innovative therapeutic strategies to reduce CV morbidity and mortality in CKD.

CureusVol. 17(11)
Mother Teresa Hospital (AL)
Openalex Percentile: Top 47%
Heart Failure Treatment and Management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.