Beyond Traditional Risk Factors: Inflammation, Asymmetric Dimethylarginine, and N-Terminal pro–B-Type Natriuretic Peptide Predict Cardiovascular Risk in Chronic Kidney Disease
Both traditional and non-traditional factors contribute to the CV burden in CKD. Biomarkers of inflammation and endothelial dysfunction (IL-6, ADMA) are independent predictors of NT-proBNP and provide prognostic value beyond classical determinants. Incorporating these biomarkers into risk stratification models may improve prediction and guide innovative therapeutic strategies to reduce CV morbidity and mortality in CKD.
Authors
- Somida Kuka
- Elizana Zaimi (ORCID: https://orcid.org/0000-0001-9033-6568)
- Ledio Collaku
- Margarita Resuli
- Eneida Hoxha
- Saimir Seferi
- Anyla Bulo
- Pandush Pojani
- Xhesika Habilaj
- Matilda Kambo
Institutions
- Mother Teresa Hospital (AL)
Publication Details
- Journal
- Cureus
- Published
- 2025-11-24
- DOI
- https://doi.org/10.7759/cureus.97654
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00