Epigenetic Reprogramming Via Sodium Butyrate Induces Corneal Myofibroblast Dedifferentiation In Vitro and Inhibits Fibrosis In Vivo
Dedifferentiation of CMFs via epigenetic reprogramming by NaB offers an attractive approach to treat corneal fibrosis in vivo. Additional studies are warranted.
Authors
- Nishant R. Sinha (ORCID: https://orcid.org/0000-0001-8358-8433)
- Anil Tiwari
- Suneel Gupta (ORCID: https://orcid.org/0000-0002-6141-3728)
- Ratnakar Tripathi
- Rajiv R. Mohan (ORCID: https://orcid.org/0000-0002-1857-4200)
- Swati Sood (ORCID: https://orcid.org/0009-0006-5024-2077)
- Eva Ruterschmidt
Institutions
- Missouri College (US)
- Harry S. Truman Memorial Veterans' Hospital (US)
- University of Missouri (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1167/iovs.66.14.59
- Citations
- 2
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- U.S. Department of Veterans Affairs
- University of Missouri
- National Institutes of Health
- National Eye Institute