Salivary Titanium Level as a Non-invasive Biomarker for Peri-Implantitis: A Prospective Study

Salivary titanium ion concentration increased with the severity of peri-implant disease and correlated with the clinical indicators of inflammation and bone resorption. This non-invasive biomarker reflects implant surface degradation and may serve as an early diagnostic tool for peri-implantitis. Regular monitoring of salivary titanium could enhance risk assessment and support timely clinical intervention, thereby improving long-term implant outcomes.

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Publication Details

Journal
Cureus
Published
2025-11-24
DOI
https://doi.org/10.7759/cureus.97643
Primary Topic
Dental Implant Techniques and Outcomes
Type
article
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0.00
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article

Salivary Titanium Level as a Non-invasive Biomarker for Peri-Implantitis: A Prospective Study

Manish Sharma, Kavita Sharma, Rahul Tiwari, Raghavendra Sumanth Phani Challa et al.
Cureus
Dental Implant Techniques and Outcomes
article

Salivary Titanium Level as a Non-invasive Biomarker for Peri-Implantitis: A Prospective Study

Manish Sharma, Kavita Sharma, Rahul Tiwari, Raghavendra Sumanth Phani Challa, H Dixit, Swati Swati, Naveen Ambata, Parween Jamil
article en

Abstract

Salivary titanium ion concentration increased with the severity of peri-implant disease and correlated with the clinical indicators of inflammation and bone resorption. This non-invasive biomarker reflects implant surface degradation and may serve as an early diagnostic tool for peri-implantitis. Regular monitoring of salivary titanium could enhance risk assessment and support timely clinical intervention, thereby improving long-term implant outcomes.

CureusVol. 17(11)
Government Medical College (IN), Holyoke Community College (US), Department of Health & Family Welfare (IN), Dr. D.Y. Patil Vidyapeeth, Pune (IN), Government Dental College and Hospital (IN), Swami Devi Dyal Hospital and Dental College (IN), MNR Dental College and Hospital (IN), Medical Research Foundation (GB)
Openalex Percentile: Top 49%
Dental Implant Techniques and Outcomes
DOIOpen Access PDFOpenAlex
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Salivary Titanium Level as a Non-invasive Biomarker for Peri-Implantitis: A Prospective Study — Manish Sharma, Kavita Sharma, et al. · Cureus (2025) | TGRS Research Map | TGRS