Prognostic and Immunological Significance of TIPARP in Pancreatic Cancer
TIPARP is a novel independent prognostic biomarker and potential therapeutic target in pancreatic cancer. It contributes to tumor progression by promoting an immunosuppressive microenvironment and activating pro-tumorigenic signaling. These findings highlight TIPARP as a promising candidate for precision medicine and combination immunotherapy in PAAD.
Authors
- Jianwu Wu (ORCID: https://orcid.org/0000-0001-7890-2379)
- Yujia Pan (ORCID: https://orcid.org/0000-0002-4658-8650)
- Hanlin Jiang
- Zongying Jiang
- Zhiming Qiao (ORCID: https://orcid.org/0000-0001-5924-4497)
- Xinwei Jiang (ORCID: https://orcid.org/0000-0003-4484-1293)
- Weiqiao Niu
- Lining Huang (ORCID: https://orcid.org/0000-0001-5754-2706)
Institutions
- Suzhou Municipal Hospital (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Digestive Diseases and Sciences
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1007/s10620-025-09546-2
- Primary Topic
- Cell death mechanisms and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00