A systematic review of structured weight loss programs and their association with HbA1c reduction in adults with prediabetes managed in primary care

Structured weight loss programs in primary care are associated with modest-to-moderate HbA1c reductions. However, study heterogeneity, analytical methods and inconsistent adherence reporting limit definitive conclusions. Future research should prioritize standardized reporting, long-term outcomes, and diverse populations to enhance generalizability.

Authors

Ayokunle Osonuga (ORCID: https://orcid.org/0000-0001-8269-6846)
Serge Engamba (ORCID: https://orcid.org/0009-0007-3425-8367)
Gloria Okoye
Adewoyin Osonuga
Nicholas Aderinto (ORCID: https://orcid.org/0000-0003-0004-7389)

Institutions

University of East Anglia (GB)
Norwich University (US)
University of Exeter (GB)
Norwich Research Park (GB)
Babcock University (NG)
Ladoke Akintola University of Technology (NG)
City College Norwich (GB)

Publication Details

Journal: Primary care diabetes
Published: 2025-11-22
DOI: https://doi.org/10.1016/j.pcd.2025.11.007
Primary Topic: Bariatric Surgery and Outcomes
Type: article
Field-Weighted Citation Impact: 0.00

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article

A systematic review of structured weight loss programs and their association with HbA1c reduction in adults with prediabetes managed in primary care

Ayokunle Osonuga, Serge Engamba, Gloria Okoye, Adewoyin Osonuga et al.

Nov 22, 2025

Primary care diabetes

Bariatric Surgery and Outcomes

article

A systematic review of structured weight loss programs and their association with HbA1c reduction in adults with prediabetes managed in primary care

Ayokunle Osonuga, Serge Engamba, Gloria Okoye, Adewoyin Osonuga, Nicholas Aderinto

November 22, 2025article en

Abstract

Structured weight loss programs in primary care are associated with modest-to-moderate HbA1c reductions. However, study heterogeneity, analytical methods and inconsistent adherence reporting limit definitive conclusions. Future research should prioritize standardized reporting, long-term outcomes, and diverse populations to enhance generalizability.

Primary care diabetesVol. 20(2)

University of East Anglia (GB), Norwich University (US), University of Exeter (GB), Norwich Research Park (GB), Babcock University (NG), Ladoke Akintola University of Technology (NG), City College Norwich (GB)

Openalex Percentile: Top 45%

Bariatric Surgery and Outcomes

DOI Open Access PDF OpenAlex

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A systematic review of structured weight loss programs and their association with HbA1c reduction in adults with prediabetes managed in primary care — Ayokunle Osonuga, Serge Engamba, et al. · Primary care diabetes (2025) | TGRS Research Map | TGRS