Integrated knowledge translation (iKT) in preclinical research: A scoping review protocol
Guided by a modified Arksey and O'Malley's scoping review framework, we will systematically search reference lists and key research databases including Medline, Embase, PsycINFO, Cochrane CENTRAL, Cochrane Database of Systematic Reviews, and Web of Science. Peer-reviewed articles written or translated in English that focus on iKT or approaches that align with iKT within the context of preclinical research will be included. This review will be conducted as part of the Improving Neuroplasticity through Spaced Prefrontal intermittent-Theta-Beta-Stimulation REfinement in Depression (INSPiRE-D) project, which features preclinical research from mouse models to human work (Grant number CAMH File No.22-060). The project's multidisciplinary team and knowledge user advisory committee will be consulted at key points throughout the scoping review process. A person with lived experience co-chairs the project advisory committee, co-authored this manuscript, and will be routinely included in the decision-making process of the scoping review.
Authors
- Daniel M. Blumberger (ORCID: https://orcid.org/0000-0002-8422-5818)
- Reena Besa (ORCID: https://orcid.org/0000-0002-1455-5483)
- Graham L. Collingridge (ORCID: https://orcid.org/0000-0002-9572-5359)
- Clement Ma
- Georgia Black (ORCID: https://orcid.org/0000-0003-2676-5071)
- Zizhen Yao (ORCID: https://orcid.org/0000-0002-9361-5607)
- Evelyn K. Lambe (ORCID: https://orcid.org/0000-0002-5994-6090)
- Sanjeev Sockalingam (ORCID: https://orcid.org/0000-0002-9626-1509)
- Branka Agic (ORCID: https://orcid.org/0000-0001-9765-1296)
- Tarek K. Rajji (ORCID: https://orcid.org/0000-0002-8324-2560)
- John Georgiou (ORCID: https://orcid.org/0000-0003-4503-6384)
- Heather Brooks (ORCID: https://orcid.org/0000-0002-2326-9729)
- Clair M. Sullivan (ORCID: https://orcid.org/0000-0003-2475-9989)
- Bernadette Mdawar (ORCID: https://orcid.org/0000-0002-2987-6917)
- Quincy Vaz
Institutions
- University Health Network (CA)
- Centre for Addiction and Mental Health (CA)
- University of Calgary (CA)
- University of Toronto (CA)
- Lunenfeld-Tanenbaum Research Institute (CA)
- Southwestern Medical Center (US)
- Occupational Cancer Research Centre (CA)
- Public Health Ontario (CA)
- The Wilson Centre (CA)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1371/journal.pone.0337202
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00