Epidemiology and Clinical Characteristics of Human Rickettsial Infections Detected in Nigeria: Discovery of a Significant Contributor to Acute Febrile Illness
This study provides the first evidence of human rickettsial infection in humans in Nigeria, with a substantial prevalence among febrile patients. The absence of classic cutaneous signs such as rash or eschar may hinder clinical recognition. Rickettsial infection should be considered in the differential diagnosis of acute febrile illness in Nigeria, and molecular diagnostics should be expanded to improve detection and guide appropriate therapy.
Authors
- Ikponmwosa Odia (ORCID: https://orcid.org/0000-0002-9393-9898)
- Jay Osi Samuels (ORCID: https://orcid.org/0000-0001-8933-1006)
- Emmanuel Oga
- Oladimeji Damilare Matthew (ORCID: https://orcid.org/0000-0001-9442-4709)
- Claire Quiner (ORCID: https://orcid.org/0000-0003-4419-1542)
- Cyril Erameh (ORCID: https://orcid.org/0000-0001-7783-2495)
- Femi Owolagba
- Kat Asman (ORCID: https://orcid.org/0000-0001-6728-4990)
- Ephraim Ogbaini-Emovon (ORCID: https://orcid.org/0000-0001-5407-1152)
- Philippe Chebu (ORCID: https://orcid.org/0009-0008-7492-670X)
- Osahogie Isaac Edeawe (ORCID: https://orcid.org/0000-0001-7424-8832)
- Lauren Courtney (ORCID: https://orcid.org/0000-0002-8943-4934)
- Vivian Kwaghe (ORCID: https://orcid.org/0000-0003-1962-4641)
- Jean Kim (ORCID: https://orcid.org/0000-0002-2207-6263)
- Adamu Zigwai Ephraim
- Jacqueline Agbukor
- Blessing Amierhobhiye Obagho
- Victoria Orok (ORCID: https://orcid.org/0009-0001-9960-8096)
- Onyia Justus Ejike (ORCID: https://orcid.org/0009-0009-9854-5853)
- Walter Mary Odion (ORCID: https://orcid.org/0009-0008-7599-5491)
- Nankpah Godsave Vongdip
- Blessed Okhiria
- Richard Fayomade
Institutions
- RTI International (US)
- Partners In Care (US)
- AIDS Prevention Initiative in Nigeria (NG)
- University of Abuja Teaching Hospital (NG)
- Irrua Specialist Teaching Hospital (NG)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1093/cid/ciaf502
- Citations
- 2
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.10