Switch from premixed insulin analogue to degludec-liraglutide combination: a CGM study

iDegLira improved glycemic control, resulting in a lower HbA1c and higher TIR, alongside beneficial effects on body weight and total daily insulin doses. While numerical reductions in hypoglycemia did not reach statistical significance, treatment was not associated with an increased risk of hypoglycemia. iDegLira can be an efficient and safe treatment option, providing simplified treatment with improved glycemic control.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-11-05
DOI
https://doi.org/10.3389/fendo.2025.1715800
Primary Topic
Diabetes Management and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Switch from premixed insulin analogue to degludec-liraglutide combination: a CGM study

Mitja Krajnc, Nika Aleksandra Kravos Tramšek, Andrijana Koceva
Frontiers in Endocrinology
Diabetes Management and Research
article

Switch from premixed insulin analogue to degludec-liraglutide combination: a CGM study

Mitja Krajnc, Nika Aleksandra Kravos Tramšek, Andrijana Koceva
article en

Abstract

iDegLira improved glycemic control, resulting in a lower HbA1c and higher TIR, alongside beneficial effects on body weight and total daily insulin doses. While numerical reductions in hypoglycemia did not reach statistical significance, treatment was not associated with an increased risk of hypoglycemia. iDegLira can be an efficient and safe treatment option, providing simplified treatment with improved glycemic control.

Frontiers in EndocrinologyVol. 16
University of Maribor (SI), University Clinical Centre Maribor (SI)
Openalex Percentile: Top 52%
Diabetes Management and Research
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