Safety and Efficacy of Ozanimod in Patients With Moderately to Severely Active Ulcerative Colitis Stratified by Age
Ozanimod safety was similar and efficacy was generally comparable across age groups, although statistical significance vs placebo was not achieved in patients >60 years of age.
Authors
- Sara Horst (ORCID: https://orcid.org/0000-0003-3585-9643)
- Adam S. Faye (ORCID: https://orcid.org/0000-0002-1571-5856)
- AnnKatrin Petersen
- Peter Miles Irving (ORCID: https://orcid.org/0000-0003-0972-8148)
- Anthony Krakovich
- Silvio Danese (ORCID: https://orcid.org/0000-0001-7341-1351)
- David T. Rubin (ORCID: https://orcid.org/0000-0001-5647-1723)
- Taku Kobayashi (ORCID: https://orcid.org/0000-0002-2073-4234)
- Garrett Lawlor (ORCID: https://orcid.org/0000-0002-1917-6626)
- Raymond Cross
- Alessandro Armuzzi (ORCID: https://orcid.org/0000-0003-1572-0118)
- Nabeel Khan (ORCID: https://orcid.org/0000-0002-5368-7518)
- Millie D. Long (ORCID: https://orcid.org/0000-0001-5983-2758)
- Ashwin N. Ananthakrishnan (ORCID: https://orcid.org/0000-0002-9436-1821)
- João Sabino (ORCID: https://orcid.org/0000-0002-8892-7075)
- Corey A. Siegel (ORCID: https://orcid.org/0000-0002-2240-6605)
- Axel Dignaß
- Anjali Jain (ORCID: https://orcid.org/0000-0001-6091-7281)
- Zhaohui Liu (ORCID: https://orcid.org/0000-0001-5490-0969)
- Irina Blumenstein
- Dong Wang (ORCID: https://orcid.org/0000-0003-4415-1102)
Institutions
- University of North Carolina at Chapel Hill (US)
- Goethe University Frankfurt (DE)
- Dartmouth–Hitchcock Medical Center (US)
- Mercy Medical Center (US)
- Humanitas University (IT)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- University of Chicago (US)
- NYU Langone Health (US)
- Massachusetts General Hospital (US)
- Bristol-Myers Squibb (United States) (US)
- University Hospital Frankfurt (DE)
- IRCCS Ospedale San Raffaele (IT)
- Philadelphia VA Medical Center (US)
- Agaplesion Markus Hospital (DE)
- Kitasato Institute Hospital (JP)
- IRCCS Humanitas Research Hospital (IT)
- Mercy Medical Center (US)
- Kitasato University (JP)
- Vanderbilt University Medical Center (US)
- KU Leuven (BE)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1093/ibd/izaf258
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00