Biochemically ‘active’ pheochromocytoma can be clinically ‘silent’

With the increasing availability of imaging techniques, pheochromocytomas are increasingly detected as incidentalomas. Pheochromocytomas can be normotensive even with significantly higher catecholamine levels and large size. Secondary diabetes mellitus can be seen in up to 50% of cases of pheochromocytomas and paraganglioma, which generally resolves after successful biochemical remission. Adequate α-blockade is preferable to prevent intra-operative haemodynamic instabilities in normotensive pheochromocytomas.

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Publication Details

Journal
Endocrinology Diabetes and Metabolism Case Reports
Published
2025-10-01
DOI
https://doi.org/10.1530/edm-25-0064
Citations
1
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
2.01
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article

Biochemically ‘active’ pheochromocytoma can be clinically ‘silent’

Saikat Mitra, Shinjan Patra, Abhishek Choube, Chandrakant Munjewar
1 citations
Endocrinology Diabetes and Metabolism Case Reports
Adrenal and Paraganglionic Tumors
2.01
article

Biochemically ‘active’ pheochromocytoma can be clinically ‘silent’

Saikat Mitra, Shinjan Patra, Abhishek Choube, Chandrakant Munjewar
article en
1 citations

Abstract

With the increasing availability of imaging techniques, pheochromocytomas are increasingly detected as incidentalomas. Pheochromocytomas can be normotensive even with significantly higher catecholamine levels and large size. Secondary diabetes mellitus can be seen in up to 50% of cases of pheochromocytomas and paraganglioma, which generally resolves after successful biochemical remission. Adequate α-blockade is preferable to prevent intra-operative haemodynamic instabilities in normotensive pheochromocytomas.

Endocrinology Diabetes and Metabolism Case ReportsVol. 2025(4)
Government Medical College (IN), Nagpur Institute of Technology (IN), All India Institute of Medical Sciences Bhopal (IN), Central India Institute of Medical Sciences (IN), All India Institute of Medical Sciences, Nagpur (IN), University of Kalyani (IN)
Openalex Percentile: Top 10%
Adrenal and Paraganglionic Tumors
2.01
DOIOpen Access PDFOpenAlex
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Biochemically ‘active’ pheochromocytoma can be clinically ‘silent’ — Saikat Mitra, Shinjan Patra, et al. · Endocrinology Diabetes and Metabolism Case Reports (2025) | TGRS Research Map | TGRS