Revealing action mechanisms of Xiaoyaosan decoction for the treatment of nonalcoholic fatty liver in mice employing tandem mass tag quantitative proteomics

The study shows that XYSD improves lipid accumulation by activating PPARα signaling pathway, and finally achieves the effect of NAFL.

Authors

Chao Sun (ORCID: https://orcid.org/0000-0003-1318-9917)
Lan Zhou (ORCID: https://orcid.org/0009-0009-8526-4753)
Jun Liang (ORCID: https://orcid.org/0000-0003-0848-5658)
Jing Wang
Wenfei Wang (ORCID: https://orcid.org/0000-0003-3360-8082)
Haifeng Jiang (ORCID: https://orcid.org/0000-0001-6105-0181)
Yage Li (ORCID: https://orcid.org/0009-0000-1679-8414)

Institutions

Northeast Agricultural University (CN)
Heilongjiang University of Chinese Medicine (CN)
Education Department of Heilongjiang Province (CN)

Publication Details

Journal: Journal of Pharmacy and Pharmacology
Published: 2025-11-24
DOI: https://doi.org/10.1093/jpp/rgaf109
Primary Topic: Peroxisome Proliferator-Activated Receptors
Type: article
Field-Weighted Citation Impact: 0.00

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article

Revealing action mechanisms of Xiaoyaosan decoction for the treatment of nonalcoholic fatty liver in mice employing tandem mass tag quantitative proteomics

Chao Sun, Lan Zhou, Jun Liang, Jing Wang et al.

Nov 24, 2025

Journal of Pharmacy and Pharmacology

Peroxisome Proliferator-Activated Receptors

article

Revealing action mechanisms of Xiaoyaosan decoction for the treatment of nonalcoholic fatty liver in mice employing tandem mass tag quantitative proteomics

Chao Sun, Lan Zhou, Jun Liang, Jing Wang, Wenfei Wang, Haifeng Jiang, Yage Li

November 24, 2025article en

Abstract

The study shows that XYSD improves lipid accumulation by activating PPARα signaling pathway, and finally achieves the effect of NAFL.

Journal of Pharmacy and PharmacologyVol. 78(2)

Northeast Agricultural University (CN), Heilongjiang University of Chinese Medicine (CN), Education Department of Heilongjiang Province (CN)

Openalex Percentile: Top 68%

Peroxisome Proliferator-Activated Receptors

DOI Source OpenAlex

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Revealing action mechanisms of Xiaoyaosan decoction for the treatment of nonalcoholic fatty liver in mice employing tandem mass tag quantitative proteomics — Chao Sun, Lan Zhou, et al. · Journal of Pharmacy and Pharmacology (2025) | TGRS Research Map | TGRS