Liquid biopsy in meningioma: a meta-analysis of diagnostic accuracy across fluid-based biomarkers
Fluid-based biomarkers show good overall accuracy for meningioma diagnosis, but the current evidence is compromised by methodological bias, suggesting that true performance is more modest than reported. Rigorous, prospective validation of promising approaches like cfDNA methylation and seroreactivity is essential to clarify their clinical utility.
Authors
- Carlos Pilotto Heming (ORCID: https://orcid.org/0000-0002-4504-7086)
- Veronica Aran (ORCID: https://orcid.org/0000-0003-2751-0986)
- Yasminn Meireles (ORCID: https://orcid.org/0009-0006-1302-9218)
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Instituto Estadual do Cérebro Paulo Niemeyer (BR)
- Universidade Federal do Estado do Rio de Janeiro (BR)
Publication Details
- Journal
- Expert Review of Molecular Diagnostics
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1080/14737159.2025.2595698
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 0.00