Evolution of pneumococcal serotype 19A in children in Bangladesh: insights from genomic analysis

This study presents the first comprehensive genomic analysis of the serotype 19A population in Bangladesh, supporting the decision to introduce PCV10 in Bangladesh based on local pneumococcal serotype burden data. However, the rapid evolution within the local 19A population highlights the need for continuous epidemiological and genomic surveillance to support effective vaccination programs.

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Publication Details

Journal
BMC Microbiology
Published
2025-11-24
DOI
https://doi.org/10.1186/s12866-025-04484-5
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
0.00

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article

Evolution of pneumococcal serotype 19A in children in Bangladesh: insights from genomic analysis

Senjuti Saha, Md Hasanuzzaman, Shampa Saha, Roly Malaker et al.
BMC Microbiology
Pneumonia and Respiratory Infections
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Evolution of pneumococcal serotype 19A in children in Bangladesh: insights from genomic analysis

Senjuti Saha, Md Hasanuzzaman, Shampa Saha, Roly Malaker, Stephanie W. Lo, Yogesh Hooda, Lesley McGee, Naito Kanon, Apurba Rajib Malaker, Hafizur Rahman, Samir K. Saha, Arif Mohammad Tanmoy, Sudipta Deb Nath, Deb Purna Keya, Mohammad Jamal Uddin, Belal Hossain, Harry C. H. Hung, Stephen D. Bentley, Esha Kazi
article en

Abstract

This study presents the first comprehensive genomic analysis of the serotype 19A population in Bangladesh, supporting the decision to introduce PCV10 in Bangladesh based on local pneumococcal serotype burden data. However, the rapid evolution within the local 19A population highlights the need for continuous epidemiological and genomic surveillance to support effective vaccination programs.

BMC MicrobiologyVol. 25(1)
Centers for Disease Control and Prevention (US), Wellcome Sanger Institute (GB), Child Health Research Foundation (BD), University of Bath (GB)
Child Health Research Foundation
Openalex Percentile: Top 53%
Pneumonia and Respiratory Infections
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