Global transcriptional regulation by the CodY gene: identification of critical compounds that enhance oxidative stress resistance in Lactobacillus delbrueckii subsp. Bulgaricus

The study results are important for understanding the synergistic effect of the two bacteria during fermentation and their response to environmental stresses. The findings provide insights into the role of CodY in modulating the oxidative-stress resistance of L. delbrueckii and highlight the potential of identified metabolites to enhance the performance of this bacterium under stress conditions. This could have implications for the development of strategies to improve the robustness of industrial fermentation processes involving these bacteria.