Repeated pseudohypoaldosteronism (PHA1) in pregnancy associated with fetal growth restriction: case report and review of the literature

To the best of our knowledge, this is the first documented case of reactivation of PHA 1 during pregnancy. The possibility that pregnancy can induce the recurrence of PHA underscores the importance of close monitoring and multidisciplinary management approach to improve maternal electrolyte complications and adverse fetal outcomes, such as growth restriction. Further studies are needed to better understand this rare phenomenon and improve care.

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Publication Details

Journal
BMC Pregnancy and Childbirth
Published
2025-11-24
DOI
https://doi.org/10.1186/s12884-025-08310-8
Primary Topic
Ion Transport and Channel Regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

Repeated pseudohypoaldosteronism (PHA1) in pregnancy associated with fetal growth restriction: case report and review of the literature

Saheed Shittu, Stephen Beer, Yehia El Khawly, Ahmed Salem et al.
BMC Pregnancy and Childbirth
Ion Transport and Channel Regulation
article

Repeated pseudohypoaldosteronism (PHA1) in pregnancy associated with fetal growth restriction: case report and review of the literature

Saheed Shittu, Stephen Beer, Yehia El Khawly, Ahmed Salem, Kholode Al-Maslamani, Hakem Nazdaf, Lolwa Alansari, Sanaa Al Hassan, Hudi Youshaa, Mohamed Abohafs
article en

Abstract

To the best of our knowledge, this is the first documented case of reactivation of PHA 1 during pregnancy. The possibility that pregnancy can induce the recurrence of PHA underscores the importance of close monitoring and multidisciplinary management approach to improve maternal electrolyte complications and adverse fetal outcomes, such as growth restriction. Further studies are needed to better understand this rare phenomenon and improve care.

BMC Pregnancy and ChildbirthVol. 25(1)
Weill Cornell Medical College in Qatar (QA), Hamad Medical Corporation (QA)
Openalex Percentile: Top 68%
Ion Transport and Channel Regulation
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Repeated pseudohypoaldosteronism (PHA1) in pregnancy associated with fetal growth restriction: case report and review of the literature — Saheed Shittu, Stephen Beer, et al. · BMC Pregnancy and Childbirth (2025) | TGRS Research Map | TGRS