Combined elevation of myeloid-derived suppressor cells and Tregs predicts lymph node metastasis in breast cancer
Elevated levels of MDSCs (and their subsets) and Tregs are closely associated with lymph node metastasis in breast cancer. Their combined detection provides an effective predictive tool for lymph node involvement and holds substantial clinical value.
Authors
- Sifan Wang (ORCID: https://orcid.org/0009-0008-0842-2044)
- Jingfu Qiu (ORCID: https://orcid.org/0000-0003-1220-7319)
- Huichao Zhang (ORCID: https://orcid.org/0000-0003-3158-9324)
- Qingjing Li
- Feng Zhao (ORCID: https://orcid.org/0000-0002-1525-042X)
- Hong Li (ORCID: https://orcid.org/0000-0001-6268-8662)
- Wei Li (ORCID: https://orcid.org/0000-0002-1732-8999)
- Xiaojie Yin
- Longfei Xia
- Yuan Song (ORCID: https://orcid.org/0000-0003-0929-8969)
Institutions
- Hebei Medical University (CN)
- Hebei Chemical and Pharmaceutical College (CN)
- Fourth Hospital of Hebei Medical University (CN)
- Central Hospital of Zibo (CN)
- Chongqing Public Health Medical Center (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1186/s12885-025-15277-4
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00