Association between prophylactic antibiotics and surgical site infections in bimaxillary orthognathic surgery: a retrospective study
Ampicillin monotherapy may be insufficient for preventing SSIs in bimaxillary orthognathic surgery. Sulbactam/ampicillin demonstrated superior efficacy, whereas cefmetazole and clindamycin showed comparable effectiveness as alternative prophylactic agents. These findings underscore the importance of selecting appropriate antibiotics to minimize postoperative infection risk.
Authors
- Yoshiko Ikeda
- Yujiro Machida
- F Toda
- Yoshiaki Horie
- Kazunori Nozaki (ORCID: https://orcid.org/0000-0003-3378-0915)
- Emiko Tanaka Isomura (ORCID: https://orcid.org/0000-0002-7855-9600)
- Yusuke Yokota (ORCID: https://orcid.org/0000-0001-9282-6544)
- Hiromi Nagashima (ORCID: https://orcid.org/0000-0003-1271-1152)
- S Seki (ORCID: https://orcid.org/0000-0001-7726-4395)
- Ryuta Urakawa (ORCID: https://orcid.org/0000-0003-0412-4118)
- Kenji Ikeda (ORCID: https://orcid.org/0000-0003-1380-4983)
- Hiroko Ueda
- Minako Ohishi (ORCID: https://orcid.org/0009-0005-1760-2379)
- Shiho Mima
Institutions
- Osaka University Hospital (JP)
- Osaka University of Pharmaceutical Sciences (JP)
- Osaka Dental University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1186/s12903-025-07246-x
- Primary Topic
- Orthodontics and Dentofacial Orthopedics
- Type
- article
- Field-Weighted Citation Impact
- 0.00