Antigen Format Determines Immunogenicity of AAV-Based SARS-CoV-2 Vaccines: Full-Length Spike Versus Truncated Subunits
Full-length Spike outperforms truncated subunits in the AAV context, highlighting antigen structure as a critical factor for next-generation coronavirus vaccine design.
Authors
- Maria E. Frolova (ORCID: https://orcid.org/0000-0002-7318-6614)
- Anna Vakhrusheva (ORCID: https://orcid.org/0000-0001-7948-1254)
- А. А. Исаев (ORCID: https://orcid.org/0000-0001-5848-5117)
Institutions
- Biotech Park (IN)
- Comet (Russia) (RU)
- Swift Engineering (United States) (US)
Publication Details
- Journal
- Vaccines
- Published
- 2025-11-24
- DOI
- https://doi.org/10.3390/vaccines13121187
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Centre