Design, synthesis, and cytotoxic evaluation of new thiosemicarbazone/thiazolidin-4-one derivatives on PC3 cells
The combined synthetic, computational, and biological results demonstrate that thiazolidin-4-one-based hybrids, particularly compound 9, are promising selective androgen receptor-targeted anticancer agents, warranting further optimization and development.
Authors
- Pelin ŞAHİN (ORCID: https://orcid.org/0000-0002-5553-9543)
- Halil Şenol (ORCID: https://orcid.org/0000-0002-8333-035X)
- Şeyma Ateşoğlu (ORCID: https://orcid.org/0000-0001-7540-1456)
- Fahri Akbaş (ORCID: https://orcid.org/0000-0002-3837-250X)
- Feyzi Sinan Tokalı
Institutions
- Kafkas University (TR)
- Bezmiâlem Vakıf Üniversitesi (TR)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1080/17568919.2025.2592533
- Citations
- 1
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 1.52