ZMIZ2/MCM3 Axis Participates in Triple-Negative Breast Cancer Progression
ZMIZ2 and MCM3 were highly expressed in TNBC. ZMIZ2 promoted the development by positively regulating MCM3 expression. Key pathways, such as the Ras/MAPK, phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mTOR, and Wnt signaling pathways, may be key downstream mechanisms.
Authors
- Jerry Yu (ORCID: https://orcid.org/0000-0002-6236-2336)
- Bingqing Nie
- Meiyang Sun
- Xiaomeng Li (ORCID: https://orcid.org/0000-0002-7811-3457)
- Xin Jiang (ORCID: https://orcid.org/0000-0002-2798-4156)
- Xiaopan Zou (ORCID: https://orcid.org/0009-0007-7447-7505)
Institutions
- Kingmed Diagnostics (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Published
- 2025-11-24
- DOI
- https://doi.org/10.32604/or.2025.066662
- Primary Topic
- Wnt/β-catenin signaling in development and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00