6‴‐Feruloylspinosin ameliorates pressure overload‐induced heart failure with comorbid insomnia through the activation of RORα
Our findings highlight 6-FS as a novel RORα activator with dual cardioprotective and sleep-enhancing benefits, offering new insights into the prevention and treatment of cardiovascular diseases with comorbid sleep disturbances.
Authors
- Junping Kou (ORCID: https://orcid.org/0000-0001-8377-915X)
- Boyang Yu (ORCID: https://orcid.org/0000-0002-1401-9250)
- Lan Gao (ORCID: https://orcid.org/0000-0002-2528-7656)
- Chenhui Du (ORCID: https://orcid.org/0000-0003-0931-8878)
- Minhui Sun
- Zhiqi Huang (ORCID: https://orcid.org/0000-0002-1506-1063)
- Xinxin Li (ORCID: https://orcid.org/0000-0002-0780-5771)
- Fang Li (ORCID: https://orcid.org/0000-0002-7617-6534)
- Yan Yan (ORCID: https://orcid.org/0000-0003-2120-4662)
- Shuaishuai Gong (ORCID: https://orcid.org/0000-0002-4563-0204)
Institutions
- China Pharmaceutical University (CN)
- Shanxi University (CN)
- Shanxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2025-11-23
- DOI
- https://doi.org/10.1111/bph.70255
- Primary Topic
- Magnolia and Illicium research
- Type
- article
- Field-Weighted Citation Impact
- 0.00