Integrated multi-omics analysis identifies key biomarkers associated with post-translational modifications and RNA methylation in clear cell renal cell carcinoma

This integrative multi-omics framework identifies PDIA3, STT3A, and USP4 as key biomarkers linked to PTMs and RNA methylation, delineating two molecular subtypes. These findings enhance understanding of ccRCC's molecular and immune landscape, offering insights for improved diagnostic and therapeutic strategie.

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Publication Details

Journal
Discover Oncology
Published
2025-11-23
DOI
https://doi.org/10.1007/s12672-025-04074-x
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Integrated multi-omics analysis identifies key biomarkers associated with post-translational modifications and RNA methylation in clear cell renal cell carcinoma

Xiuwang Wei, Yongzhi He, Taisen Pang
Discover Oncology
Ferroptosis and cancer prognosis
article

Integrated multi-omics analysis identifies key biomarkers associated with post-translational modifications and RNA methylation in clear cell renal cell carcinoma

Xiuwang Wei, Yongzhi He, Taisen Pang
article en

Abstract

This integrative multi-omics framework identifies PDIA3, STT3A, and USP4 as key biomarkers linked to PTMs and RNA methylation, delineating two molecular subtypes. These findings enhance understanding of ccRCC's molecular and immune landscape, offering insights for improved diagnostic and therapeutic strategie.

Discover OncologyVol. 16(1)
The People's Hospital of Guangxi Zhuang Autonomous Region (CN)
Openalex Percentile: Top 49%
Ferroptosis and cancer prognosis
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