Efficacy and safety of intrathecal human umbilical cord-derived mesenchymal stromal cell therapy for bone cancer pain: a preclinical study
Intrathecal hUC-MSC therapy demonstrates marked analgesic efficacy and a favorable safety profile in BCP, showing strong potential for clinical translation. This preclinical study provides compelling evidence to support future clinical trials and therapeutic applications of hUC-MSC therapy for BCP.
Authors
- Jing Zhang (ORCID: https://orcid.org/0000-0002-1156-9935)
- Yunqi Li
- Mengna Jiang
- Ping Wu (ORCID: https://orcid.org/0000-0001-7902-2875)
- Penghui Ren
- Qingping Wen
Institutions
- Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-11-23
- DOI
- https://doi.org/10.1186/s13287-025-04820-6
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00