Radiation De-Escalation in Older Women with Early-Stage ER+/HER2– Invasive Breast Cancer
Despite efforts to promote treatment de-escalation, rates for omission of post-lumpectomy radiotherapy have decreased over time. To avoid overtreatment, patients who are eligible for omission but opt to receive radiotherapy should be considered for PB or UHF radiotherapy regimens.
Authors
- Samantha Thomas (ORCID: https://orcid.org/0000-0001-6448-0830)
- Lesly A. Dossett (ORCID: https://orcid.org/0000-0001-8060-1073)
- Ton Wang (ORCID: https://orcid.org/0000-0003-0437-3771)
- Jennifer Kay Plichta (ORCID: https://orcid.org/0000-0002-7411-0558)
- Akiko Chiba (ORCID: https://orcid.org/0000-0003-0303-2799)
- Maggie Lee DiNome (ORCID: https://orcid.org/0000-0002-1926-292X)
- Drew Neish
- Gayle DiLalla (ORCID: https://orcid.org/0000-0002-0962-6734)
- Astrid Botty van den Bruele
- Laura Horst Rosenberger (ORCID: https://orcid.org/0000-0002-6829-6747)
- D.N. Ayala-Peacock (ORCID: https://orcid.org/0000-0002-8032-4499)
- E. Shelley Hwang
- Kendra J. Modell Parrish
Institutions
- Duke University (US)
- Michigan Medicine (US)
- Duke Medical Center (US)
- Duke University Hospital (US)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2025-11-23
- DOI
- https://doi.org/10.1245/s10434-025-18746-z
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Comprehensive Cancer Network
- National Institutes of Health
- National Cancer Institute
- Duke Cancer Institute