Ortopedi Hekimlerinin Sıkça Reçetelendirilen Nonsteroidal Anti-inflamatuar İlaçlara Bağlı Gelişen Aşırı Duyarlılık Reaksiyonlarına Yaklaşımları ve Bilgi Seviyeleri

Aim: To investigate the knowledge level about NSAIDs hypersensitivity of orthopedic surgeons who very commonly prescribe NSAIDs in their clinical practice and their approach in case of development of hypersensitivity reactions (HRs) to NSAIDs in their patients. Method: Participants were asked to complete a structured online survey which contained questions about demographic features of them and knowledge level and attitude about NSAIDs HRs. Results: One-hundred-nine orthopedic surgeons were included in the study. The mean age of the participants was 40.53±7.88 years and they have been working on orthopedic field for the mean 15.02±8.28 years. The physicians examined median (min-max) 30 (2-130) patients and prescribed median (min-max) 10 (1-60) NSAIDs per day. Forty-eight (44%) participants observed hypersensitivity reactions to NSAIDs in their patients. 32.1% of them suggested to stop the culprit NSAID and consulted to an allergist and 28.6% of them suggested to stop the culprit NSAID and recommended different treatment modalities, respectively. In the comparison of the groups of well- and poor-approach, regarding the duration of working on orthopedic field, academic degree, types of trained for orthopedic and currently worked hospital, the presence of pediatric or adult allergy clinic in medical faculty of medicine, trained and currently worked hospital, no association was observed (p>0.05). Only 4 and 1 physicians correctly answered the questions about underlying mechanism and classification. Conclusion: The present study indicated that among orthopedic surgeons the knowledge level about NSAID HRs was low and approach to the patients whom NSAID HRs developed was inadequate among orthopedic surgeons.