Real-World Enfortumab Vedotin ± Pembrolizumab Treatment-Based Toxicities and Associations With Survival in Advanced Urothelial Carcinoma

These findings highlight the clinical relevance of EV ± P related toxicities, demonstrate the importance of accounting for immortal time bias in associations of these toxicities with survival, and add to a growing evidence base showing a survival association with skin toxicity in EV ± P treated patients. Future prospective studies are needed to evaluate skin toxicity as a favorable marker for survival.

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Publication Details

Journal
Clinical Genitourinary Cancer
Published
2025-11-23
DOI
https://doi.org/10.1016/j.clgc.2025.102474
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-World Enfortumab Vedotin ± Pembrolizumab Treatment-Based Toxicities and Associations With Survival in Advanced Urothelial Carcinoma

Martin Kurian, Vivek Nimgaonkar, Ronac Mamtani, Omar Elghawy
Clinical Genitourinary Cancer
Bladder and Urothelial Cancer Treatments
article

Real-World Enfortumab Vedotin ± Pembrolizumab Treatment-Based Toxicities and Associations With Survival in Advanced Urothelial Carcinoma

Martin Kurian, Vivek Nimgaonkar, Ronac Mamtani, Omar Elghawy
article en

Abstract

These findings highlight the clinical relevance of EV ± P related toxicities, demonstrate the importance of accounting for immortal time bias in associations of these toxicities with survival, and add to a growing evidence base showing a survival association with skin toxicity in EV ± P treated patients. Future prospective studies are needed to evaluate skin toxicity as a favorable marker for survival.

Clinical Genitourinary CancerVol. 24(1)
Hospital of the University of Pennsylvania (US), Johns Hopkins Hospital (US)
Openalex Percentile: Top 45%
Bladder and Urothelial Cancer Treatments
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