Single-nucleus transcriptomics of spinal ependymoma subtypes recognizes intratumoral heterogeneity

Single-nucleus transcriptomic sequencing provides valuable insights into the molecular composition of spinal ependymoma types and subtypes and may pave the way for a better understanding of tumor evolution and identification of therapeutic targets.

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Publication Details

Journal
Neuro-Oncology
Published
2025-09-09
DOI
https://doi.org/10.1093/neuonc/noaf210
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Single-nucleus transcriptomics of spinal ependymoma subtypes recognizes intratumoral heterogeneity

Catena Kresbach, Christian Thomas, Melanie Schoof, Saskia-Larissa Jauch-Speer et al.
Neuro-Oncology
Glioma Diagnosis and Treatment
article

Single-nucleus transcriptomics of spinal ependymoma subtypes recognizes intratumoral heterogeneity

Catena Kresbach, Christian Thomas, Melanie Schoof, Saskia-Larissa Jauch-Speer, Ulrich Schüller, Karoline Hack
article en

Abstract

Single-nucleus transcriptomic sequencing provides valuable insights into the molecular composition of spinal ependymoma types and subtypes and may pave the way for a better understanding of tumor evolution and identification of therapeutic targets.

Neuro-OncologyVol. 28(1)
Universität Hamburg (DE), University Hospital Münster (DE), University Medical Center Hamburg-Eppendorf (DE), Kinderkrebs-Zentrum Hamburg (DE), Cancer Research Institute of the Slovak Academy of Sciences (SK), University Cancer Center Hamburg (DE)
Openalex Percentile: Top 48%
Glioma Diagnosis and Treatment
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