Immune Profiling in Early Cognitive Disorders (IMPRINT) study protocol: a longitudinal cohort study exploring biomarkers of inflammation in early dementia with Lewy bodies and Alzheimer’s disease, as part of the Dementias Platform UK
This study was approved by the Preston North West Research Ethics committee (21/NW/0314) and is registered with the ISRCTN registry (ISRCTN62392656). The study is ongoing (since June 2022). Baseline visits are being undertaken, and follow-up visits have started for some participants. Full data analyses will be completed and submitted for publication upon conclusion of the study.
Authors
- Gabrielle Grey
- Lina Aimola
- Elena Vila Herrero
- Leonidas Chouliaras (ORCID: https://orcid.org/0000-0002-3052-3879)
- John T. O’Brien (ORCID: https://orcid.org/0000-0002-0837-5080)
- George Savulich (ORCID: https://orcid.org/0000-0002-6513-5454)
- Harry Crook (ORCID: https://orcid.org/0000-0002-6206-470X)
- James Benedict Rowe (ORCID: https://orcid.org/0000-0001-7216-8679)
- Paresh Malhotra (ORCID: https://orcid.org/0000-0002-1897-0780)
- Anna McKeever (ORCID: https://orcid.org/0000-0001-8449-5976)
- Stacey L. Kigar (ORCID: https://orcid.org/0000-0003-2636-0648)
- Haddy K. S. Fye (ORCID: https://orcid.org/0000-0001-5597-3975)
- D. Blackburn (ORCID: https://orcid.org/0000-0001-8886-1283)
- Paul M. Matthews (ORCID: https://orcid.org/0000-0002-1619-8328)
- Peter Swann
- Lordina Turner
- Li Su (ORCID: https://orcid.org/0000-0002-6347-3986)
Institutions
- MRC Cognition and Brain Sciences Unit (GB)
- University of Cambridge (GB)
- Rosalind Franklin Institute (GB)
- UK Dementia Research Institute (GB)
- Imperial College London (GB)
- Medical Research Council (GB)
- University of Sheffield (GB)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1136/bmjopen-2025-107399
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00