Immediate Postoperative <scp>cfDNA</scp> Elevation Predicts Pain After Robot‐Assisted Radical Prostatectomy
Immediate postoperative cfDNA is significantly associated with postoperative pain severity and may serve as a rapid, sensitive biomarker for early pain prediction. The cfDNA ratio could support the development of personalized perioperative pain-management strategies. A prospective validation is warranted.
Authors
- Hirotake Kodama (ORCID: https://orcid.org/0000-0002-5071-5149)
- Shingo Hatakeyama (ORCID: https://orcid.org/0000-0002-0026-4079)
- Satoko Minakawa (ORCID: https://orcid.org/0000-0001-5933-3377)
- Teppei Okamoto (ORCID: https://orcid.org/0000-0002-3750-3811)
- Sakae Konishi
- Jotaro Mikami
- Naoki Fujita (ORCID: https://orcid.org/0000-0001-8284-9582)
- Takuma Narita (ORCID: https://orcid.org/0000-0003-2572-3590)
- Chikara Οhyama (ORCID: https://orcid.org/0000-0003-1550-8379)
- Tohru Yoneyama
- Noritaka Ishii
- Atsushi Imai (ORCID: https://orcid.org/0000-0001-7691-4982)
- Hayato Yamamoto
Institutions
- Hirosaki University (JP)
- Hirosaki University Hospital (JP)
Publication Details
- Journal
- International Journal of Urology
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1111/iju.70297
- Primary Topic
- Pain Management and Opioid Use
- Type
- article
- Field-Weighted Citation Impact
- 0.00