Aetiological clustering of newly diagnosed type 2 diabetes using machine learning: a retrospective cross-sectional study in Dubai, UAE

The study confirms that both severe and mild T2D phenotypes are present in newly diagnosed, complication-free patients, supporting the applicability of cluster-based classification early in disease. These results highlight the potential for personalised treatment strategies to optimise management and prevent complications. Future studies should investigate longitudinal outcomes and therapeutic response across clusters.

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Publication Details

Journal
BMJ Open
Published
2025-11-01
DOI
https://doi.org/10.1136/bmjopen-2025-101284
Primary Topic
Diabetes and associated disorders
Type
article
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0.00
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article

Aetiological clustering of newly diagnosed type 2 diabetes using machine learning: a retrospective cross-sectional study in Dubai, UAE

Stafny Dsouza, Riad Bayoumi, Fatima Sulaiman, Nandu Goswami et al.
BMJ Open
Diabetes and associated disorders
article

Aetiological clustering of newly diagnosed type 2 diabetes using machine learning: a retrospective cross-sectional study in Dubai, UAE

Stafny Dsouza, Riad Bayoumi, Fatima Sulaiman, Nandu Goswami, Fayha Salah Ahmed, Niaz Ali, Fahad Mulla, Amar Hassan Khamis, Ahmad A. Abdul-Aziz, M. Al-Sharhan, A Rafie, Suhaila Alnuaimi, Ayesha AlOlama, Fatima Abdul
article en

Abstract

The study confirms that both severe and mild T2D phenotypes are present in newly diagnosed, complication-free patients, supporting the applicability of cluster-based classification early in disease. These results highlight the potential for personalised treatment strategies to optimise management and prevent complications. Future studies should investigate longitudinal outcomes and therapeutic response across clusters.

BMJ OpenVol. 15(11)
Dubai Health Authority (AE), Dubai Hospital (AE), Mohammed Bin Rashid University of Medicine and Health Sciences (AE), Primary HealthCare (MT)
Openalex Percentile: Top 62%
Diabetes and associated disorders
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