Moxibustion Regulates Amino Acid Metabolism Pathways to Improve Cartilage Damage in Knee Osteoarthritis Model Rats
Moxibustion at ST36 can significantly improve joint swelling, pain, synovitis, and chondrocyte injury in rats with KOA. It modulates immune response and cartilage synthesis and degradation through alanine, aspartate, and glutamate metabolic pathways, thereby exerting anti-inflammatory, analgesic, and protective effects on cartilage injury.
Authors
- Chien‐Chi Lin (ORCID: https://orcid.org/0000-0002-4175-8796)
- Gao Zi Zhan
- Jian Wu (ORCID: https://orcid.org/0000-0001-7065-9917)
- Qing Yu (ORCID: https://orcid.org/0000-0003-2837-121X)
- Jie Wang (ORCID: https://orcid.org/0000-0002-9376-3861)
- Lei Liu (ORCID: https://orcid.org/0009-0001-5774-978X)
- Wei Xia (ORCID: https://orcid.org/0000-0001-6182-9806)
- Duan Wen Xiu
Institutions
- Huaibei Normal University (CN)
- Hubei University of Chinese Medicine (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Huaibei Mining (China) (CN)
- Huaian First People’s Hospital (CN)
Publication Details
- Journal
- Cureus
- Published
- 2025-11-22
- DOI
- https://doi.org/10.7759/cureus.97527
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00