Radiotherapy and survival in elderly grade 4 glioma patients: The prognostic value of onco-functional outcome
OFO classification effectively stratifies survival in elderly grade 4 glioma patients. Its integration with MGMT methylation status and RT regimen refines risk assessment, supporting personalized treatment strategies in this vulnerable patient group.
Authors
- Chiara Negwer (ORCID: https://orcid.org/0000-0003-2997-969X)
- Meike Mitsdoerffer (ORCID: https://orcid.org/0000-0002-5260-9956)
- Claire Delbridge (ORCID: https://orcid.org/0000-0003-4339-6917)
- Kai Joachim Borm (ORCID: https://orcid.org/0009-0005-8580-890X)
- Benedikt Wiestler (ORCID: https://orcid.org/0000-0002-2963-7772)
- Friederike Schmidt‐Graf (ORCID: https://orcid.org/0000-0002-3515-4427)
- Helen X. Hou (ORCID: https://orcid.org/0009-0007-3326-4319)
- Stephanie Elisabeth Combs (ORCID: https://orcid.org/0000-0002-6934-2864)
- Arthur Wagner (ORCID: https://orcid.org/0000-0001-9947-2240)
- Denise Bernhardt (ORCID: https://orcid.org/0000-0001-5231-9097)
- Jan Caspar Peeken (ORCID: https://orcid.org/0000-0003-2679-9853)
- Igor Yakushev (ORCID: https://orcid.org/0000-0003-4764-798X)
- Christian Diehl (ORCID: https://orcid.org/0000-0003-1324-8999)
- Sophia M. Leiss (ORCID: https://orcid.org/0009-0007-4463-5314)
- Daniel Schmottermeyer
Institutions
- TUM Klinikum (DE)
- German Marine Research Consortium (DE)
- Institute of Groundwater Ecology (DE)
- Deutsches Konsortium für Translationale Krebsforschung (DE)
- Technical University of Munich (DE)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1016/j.ctro.2025.101085
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00