A Randomised, Double-Blind Study Comparing the Gastrointestinal Tolerability of Tegomil Fumarate Versus Dimethyl Fumarate in Healthy Volunteers
The between-group difference for the AUC of MOGISS abdominal pain score was not statistically different. However, compared with DMF, TMF showed improved GI tolerability profile in terms of self-assessed GI events and GI AEs leading to discontinuation.
Authors
- Abdelkarim Bendarraz
- Marlene Fonseca (ORCID: https://orcid.org/0009-0000-5828-8535)
- Vikas Sharma (ORCID: https://orcid.org/0009-0009-1458-6085)
- C Flores (ORCID: https://orcid.org/0009-0004-8263-7167)
- Gabriel Bauzà Valverde
Institutions
- Universidade do Estado do Rio de Janeiro (BR)
- Hospital Prof. Dr. Fernando Fonseca (PT)
- Neuraxpharm (Spain) (ES)
Publication Details
- Journal
- Neurology and Therapy
- Published
- 2025-11-23
- DOI
- https://doi.org/10.1007/s40120-025-00863-2
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Neuraxpharm