Therapeutic Effects of Probiotics on Symptoms of Anxiety in Children and Adolescents: A Systematic Review and Meta-Analysis of Placebo-Controlled Trials
Our results showed efficacy of probiotics against anxiety compared with placebos only in participants diagnosed with neurodevelopmental disorders, especially ASD. Nevertheless, insufficient evidence derived from limited studies (i.e., three trials for ASD and two for ADHD) requires further investigations for verification.
Authors
- Cheuk‐Kwan Sun (ORCID: https://orcid.org/0000-0002-2524-9684)
- Shun-Chin Liang
- Yu‐Shian Cheng (ORCID: https://orcid.org/0000-0002-7665-6642)
- Y. Edward Wen (ORCID: https://orcid.org/0000-0002-7376-0014)
- Kuo-Chuan Hung (ORCID: https://orcid.org/0000-0002-4507-8085)
Institutions
- Chung Hwa University of Medical Technology (TW)
- Kun Shan University (TW)
- Chang Bing Show Chwan Memorial Hospital (TW)
- Chi Mei Medical Center (TW)
- Chest Hospital, Ministry of Health and Welfare (TW)
- I-Shou University (TW)
Publication Details
- Journal
- Journal of Child and Adolescent Psychopharmacology
- Published
- 2025-11-23
- DOI
- https://doi.org/10.1177/10445463251399491
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.00