Prefrontal neurophysiological changes associated with subanesthetic esketamine accelerating mice emergence from propofol anesthesia
Our findings suggest that low-dose esketamine facilitates mice awakening from propofol anesthesia may by orchestrating a sequence of neural events in the PFC. This study provides novel mechanistic insight into the paradoxical emergence from anesthesia induced by subanesthetic esketamine/ketamine.
Authors
- Su Tang (ORCID: https://orcid.org/0000-0002-6993-1212)
- Xuliang Jiang (ORCID: https://orcid.org/0000-0003-0136-3092)
- Jun Zhang (ORCID: https://orcid.org/0000-0002-3197-0427)
- Yinying Sun
- Jia‐Yi Zhang (ORCID: https://orcid.org/0000-0001-9301-648X)
- Bo Li (ORCID: https://orcid.org/0000-0002-9498-6389)
- Yi‐Ting Wang (ORCID: https://orcid.org/0000-0003-2008-4435)
Institutions
- Fudan University (CN)
- Fudan University Shanghai Cancer Center (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-11-22
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111648
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00