Colostrum from MERS-CoV seropositive camels for MERS prophylaxis and SARS-CoV-2 infection, a placebo controlled randomized trial
In-vitro, camel colostrum-derived antibodies neutralize MERS-CoV, but a thin colostrum preparation did not reduce infectivity or viral load in SARS-CoV-2 infected individuals. The role of camel colostrum-derived antibody-concentrate and more viscous preparations merit further evaluation as potential prophylaxis and treatment against MERS-CoV.
Authors
- Daniel Grupel (ORCID: https://orcid.org/0000-0002-8315-1204)
- Reuven Wiener (ORCID: https://orcid.org/0000-0002-4219-550X)
- Jacob Strahilevitz (ORCID: https://orcid.org/0000-0002-9192-7164)
- Matan Golan (ORCID: https://orcid.org/0000-0003-4861-5912)
- Yonatan Oster (ORCID: https://orcid.org/0000-0002-1050-1648)
- Alexander Rouvinski (ORCID: https://orcid.org/0000-0002-9917-7564)
- Hila Elinav (ORCID: https://orcid.org/0000-0001-9046-8130)
- Einav Cohen‐Kfir (ORCID: https://orcid.org/0000-0002-1301-1142)
- Meir Cherniak
- Orna Mor (ORCID: https://orcid.org/0000-0003-3207-4226)
- Dan David (ORCID: https://orcid.org/0000-0002-2561-6499)
- Jamal Fahoum (ORCID: https://orcid.org/0000-0002-0631-6503)
- Elena Britan‐Rosich (ORCID: https://orcid.org/0000-0002-4655-4645)
- Moshe Dessau (ORCID: https://orcid.org/0000-0002-1954-3625)
- Hagit Masika
- Ahmad Nama
- Joel Alter (ORCID: https://orcid.org/0000-0002-1310-4867)
- Eitan Israeli
- Batel Nissan
- David Planer (ORCID: https://orcid.org/0000-0001-6699-689X)
- Saveliy Kirillov
- Sujata Kumari
- Reaan Amer
Institutions
- Bar-Ilan University (IL)
- Tel Aviv University (IL)
- Hebrew University of Jerusalem (IL)
- Hadassah Medical Center (IL)
- Soroka Medical Center (IL)
- Israel Ministry of Health (IL)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-11-22
- DOI
- https://doi.org/10.1038/s41598-025-26000-5
- Citations
- 1
- Primary Topic
- Animal health and immunology
- Type
- article
- Field-Weighted Citation Impact
- 2.35