Apoptosis-inducing factor mitochondria-associated 2 (AIFM2) promotes tumor progression and predicts poor prognosis in oral squamous cell carcinoma

AIFM2 acts as an oncogenic driver in OSCC, regulated by tumor-suppressive miR-32-5p and miR-432-5p, and serves as a potential prognostic biomarker and therapeutic target.

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Publication Details

Journal
Journal of Dental Sciences
Published
2025-11-22
DOI
https://doi.org/10.1016/j.jds.2025.11.007
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Apoptosis-inducing factor mitochondria-associated 2 (AIFM2) promotes tumor progression and predicts poor prognosis in oral squamous cell carcinoma

Chung‐Hsien Chou, Minghui Wei, Kuo-Wei Chang, Chung‐Ji Liu et al.
Journal of Dental Sciences
Ferroptosis and cancer prognosis
article

Apoptosis-inducing factor mitochondria-associated 2 (AIFM2) promotes tumor progression and predicts poor prognosis in oral squamous cell carcinoma

Chung‐Hsien Chou, Minghui Wei, Kuo-Wei Chang, Chung‐Ji Liu, Wan-Wen Hung, Shu-Chun Lin
article en

Abstract

AIFM2 acts as an oncogenic driver in OSCC, regulated by tumor-suppressive miR-32-5p and miR-432-5p, and serves as a potential prognostic biomarker and therapeutic target.

Journal of Dental SciencesVol. 21(1)
National Yang Ming Chiao Tung University (TW), Mackay Memorial Hospital (TW), Taipei Veterans General Hospital (TW)
Openalex Percentile: Top 49%
Ferroptosis and cancer prognosis
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