Renal AA amyloidosis following COVID-19 infection

Primarily a respiratory illness, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has a range of extra-pulmonary involvement, including the kidneys, which are often affected. This infection has been associated with the overproduction of serum amyloid A protein, resulting in systemic AA amyloidosis. We report a case of renal AA amyloidosis presenting as a nephrotic syndrome in a patient without any underlying risk factor except COVID-19 infection. This article offers preliminary insights into a potential connection between this emerging viral disease and this complication, awaiting confirmation through future research.

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Publication Details

Journal
Néphrologie & Thérapeutique
Published
2025-10-01
DOI
https://doi.org/10.1684/ndt.2025.151
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Renal AA amyloidosis following COVID-19 infection

Said Aissa Khelifa, T. Ben Achour, I. Naceur, Maysam Jridi et al.
Néphrologie & Thérapeutique
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Renal AA amyloidosis following COVID-19 infection

Said Aissa Khelifa, T. Ben Achour, I. Naceur, Maysam Jridi, Monia Smiti, Fatma Said
article en

Abstract

Primarily a respiratory illness, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has a range of extra-pulmonary involvement, including the kidneys, which are often affected. This infection has been associated with the overproduction of serum amyloid A protein, resulting in systemic AA amyloidosis. We report a case of renal AA amyloidosis presenting as a nephrotic syndrome in a patient without any underlying risk factor except COVID-19 infection. This article offers preliminary insights into a potential connection between this emerging viral disease and this complication, awaiting confirmation through future research.

Néphrologie & ThérapeutiqueVol. 21(6)
Hôpital La Rabta (TN)
Openalex Percentile: Top 68%
Amyloidosis: Diagnosis, Treatment, Outcomes
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